Warfarin for multiple sclerosis?

摘要

In 1983, Poser et al. Established their criteria for the diagnosis of multiple sclerosis (MS). In the same year, Hughes described the association between thrombosis, abortion, cerebral disease and lupus anticoagulant. These reports have eventually become connected. Today, almost 20 years later, there are enough data to consider antiphospholipid syndrome (APS), or Hughes' syndrome, as a major differential in the diagnosis of definite or probable MS according to Poser's criteria.