The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants

Karsten M. Wicke; Andre Rex; Ana Jongen-Relo; Ilona Groth; Gerhard Gross

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The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants

机译：豚鼠强迫游泳测试是一种新型的行为绝望模型，用于表征潜在的抗抑郁药

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Behavioral despair is a model of high predictivity for antidepressant activity in murids. For some drug targets, guinea pigs exhibit a higher homology to their human counterparts compared to murids.

机译：行为绝望是模型的高度预测性在小鼠中的抗抑郁活性。对于某些药物靶标，豚鼠与杂种豚鼠相比，它们的人类同源性更高。

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来源
《Psychopharmacology》 |2007年第1期|95-102|共8页
作者
Karsten M. Wicke; Andre Rex; Ana Jongen-Relo; Ilona Groth; Gerhard Gross;
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作者单位

Neuroscience Discovery Research Abbott 67008 Ludwigshafen Germany;

Institute of Pharmacology and Toxicology School of Veterinary Medicine Freie Universität Berlin 14195 Berlin Germany;

Neuroscience Discovery Research Abbott 67008 Ludwigshafen Germany;

Neuroscience Discovery Research Abbott 67008 Ludwigshafen Germany;

Neuroscience Discovery Research Abbott 67008 Ludwigshafen Germany;

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原文格式 PDF
正文语种 eng
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关键词
Depression; Guinea pig; Forced swim test; Antidepressants; Neurokinin 1 receptor antagonist;

机译：抑郁;几内亚猪;强迫游泳试验;抗抑郁药;神经激肽1受体拮抗剂;

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1. The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants. [J] . Wicke KM, Rex A, Jongen-Relo A, Psychopharmacology . 2007,第1期

机译：豚鼠强迫游泳试验是一种新型的绝望行为模型，用于表征潜在的抗抑郁药。
2. Stressors affect the response of male and female rats to clomipramine in a model of behavioral despair (forced swim test). [J] . Consoli D, Fedotova J, Micale V, European Journal of Pharmacology: An International Journal . 2005,第1a3期

机译：在行为绝望模型（强迫游泳试验）中，压力源会影响雄性和雌性大鼠对氯米帕明的反应。
3. INFLUENCE OF THE BRAIN SEXUAL DIFFERENTIATION PROCESS ON DESPAIR AND ANTIDEPRESSANT-LIKE EFFECT OF FLUOXETINE IN THE RAT FORCED SWIM TEST [J] . M. L. GOMEZ, L. MARTINEZ-MOTA, E. ESTRADA-CAMARENA, Neuroscience: An International Journal under the Editorial Direction of IBRO . 2014,第Null期

机译：强制性游泳试验中脑性别分化过程对氟西汀脱水和抗抑郁样作用的影响
4. Total Phenolic, UPLC-QTOF-MS Analysis and Antidepressant-like Effect in The Mice Forced Swim Test of Jamu Neuropathic Pain Reducer [C] . Aisyah Hanifah, Dewi Tristantini International Symposium of Biomedical Engineering . 2019

机译：在Jamu神经病变减速剂的小鼠强制游泳试验中，全酚类酚类，UPLC-QTOF-MS分析和抗抑郁效果
5. Protein kinase A and the forced swim test: A strain comparison. [D] . Rogacki, Nancy. 2006

机译：蛋白激酶A和强迫游泳测试：菌株比较。
6. Impact of maternal melatonin suppression on forced swim and tail suspension behavioral despair tests in adult offspring [O] . SE Voiculescu, AE Rosca, V Zeca, 2015

机译：产妇褪黑激素抑制对成年后代强迫游泳和尾巴悬吊行为绝望测试的影响
7. Modulatory effect of cilostazol on tramadol-induced behavioral and neurochemical alterations in rats challenged across the forced swim despair test [O] . Noha M. Gamil, Yousreya A. Maklad, Maha A.E. Ahmed, 2016

机译：西洛他唑对曲马多诱导的大鼠行为和神经化学改变的调节作用在强迫游泳绝望试验中受到挑战

The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants

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