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Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

机译:DAI(DLM-1 / ZBP1)和其他DNA感应分子对先天免疫应答的调节

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摘要

DNA, whether it is microbe-derived or host-derived, evokes immune responses when exposed to the cytosol of a cell. We previously reported that DNA-dependent activator of IFN regulatory factors (DAI), also referred to as DLM-1/ZBP1, functions as a DNA sens
机译:DNA,无论是微生物来源还是宿主来源,当暴露于细胞的细胞质时都会引发免疫反应。我们之前曾报道过,IFN调节因子(DAI)的DNA依赖性激活剂,也称为DLM-1 / ZBP1,起着DNA感觉的作用。

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