Industrial Production Technology for High Molecular Weight Polyglycolic Acid

摘要

We have established the world's first industrial scale production technology of high molecular weight polyglycolic acid (PGA). The technology employs the ring-opening polymerization process of glycolide (GL). However, traditional GL synthesis by bulk depolymerization of glycolic acid oligomer has proven industrially limited due to both poor yields and low purity from undesirable side reactions. Our innovation, which utilizes an innovated solvent for GL synthesis, resolves past yield and purity deficiencies allowing a scalable production method.