Spectroscopic study on the inclusion complexation of L-tyrosine by p-sulphonatocalix[6]arene at different pH values

摘要

The inclusion complexation behaviour of L-tyrosine(L-Tyr) guest molecule with p-sulphonatocalix[6]arene (C6AS) molecular receptor has been investigated by fluorescence and nuclear magnetic resonance (NMR) spectroscopy. Experimental results showed that C6AS forms 1 : 1 complexes with L-Tyr in water. Their stability constant determined by pectrofluorometric titration is 18,622 L mol−1. 1H NMR studies displayed that L-Tyr is encapsulated into the hydrophobic cavity of C6AS. In addition, the thermodynamic parameters for the complexation of C6AS with L-Tyr were determined by Van’t Hoff analysis. The obtained data further confirmed the binding mode of C6AS with L-Tyr. The related mechanism is proposed to explain the complexation processes.View full textDownload full textKeywordssupramolecular chemistry, aromatic L-tyrosine, water-soluble calix[6]arene, spectrofluorometryRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/00319104.2011.646445