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首页> 外文期刊>Photonics Journal, IEEE >Label-Free Biosensing With a Slot-Waveguide-Based Ring Resonator in Silicon on Insulator
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Label-Free Biosensing With a Slot-Waveguide-Based Ring Resonator in Silicon on Insulator

机译:绝缘子上的硅中具有基于槽波导的环形谐振器的无标签生物传感

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摘要

We present a slot-waveguide-based ring resonator in silicon on insulator (SOI) with a footprint of only 13 mum times 10 mum, fabricated with optical lithography. Experiments show that it has 298 nm/RIU sensitivity and a detection limit of 4.2middot10-5 RIU for changes in the refractive index of the top cladding. We prove for the first time that surface chemistry for selective label-free sensing of proteins can be applied inside a 100 nm-wide slot region and demonstrate that the application of a slot waveguide instead of a normal waveguide increases the sensitivity of an SOI ring resonator with a factor 3.5 for the detection of proteins.
机译:我们介绍了一种在绝缘体上硅(SOI)中基于狭缝波导的环形谐振器,其占地面积仅为13微米乘以10微米,是通过光刻技术制造的。实验表明,它具有298 nm / RIU的灵敏度和4.2 dotdot10-5 RIU的检测极限,可改变顶部包层的折射率。我们首次证明可以在100 nm宽的缝隙区域内应用用于蛋白质的选择性无标记传感的表面化学,并证明使用缝隙波导代替普通波导可以提高SOI环形谐振器的灵敏度具有3.5的蛋白质​​检测因子。

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