Response to Comments by Sayre, Dowdy and Stanfield on our Article Entitled 'Algorithm for in vitro Sun Protection Factor Based on Transmission Spectrum Measurement with Concomitant Evaluation of Photostability.' Photochem. Photobiol. (2008)

摘要

[...] we are pleased to note that they agree with our comment that it would be preferable to use an application dose of 2.00 mg cm^sup -2^, as in in vivo SPF measurement, stating that "the application amount for in vitro sunscreen evaluations should be 2 mg cm^sup -2^ as used in the human SPF test, because photostability testing on thinner layers of sunscreen product, as many methods have utilized, may underestimate product photostability of the thicker films associated with human SPF testing." [...] we have already reported that in vitro SPF evaluation among various types of formulation with the application dose of 2 mg cm^sup -2^ shows a good correlation with in vivo SPF value, in me IFSCC Congress 2009 in Barcelona (3).