首页> 外文期刊>Pharmaceutical Research >Preparation, Characterization of 2-Deoxy-D-Glucose Functionalized Dimercaptosuccinic Acid-Coated Maghemite Nanoparticles for Targeting Tumor Cells
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Preparation, Characterization of 2-Deoxy-D-Glucose Functionalized Dimercaptosuccinic Acid-Coated Maghemite Nanoparticles for Targeting Tumor Cells

机译:靶向肿瘤细胞的2-脱氧-D-葡萄糖功能化二巯基琥珀酸涂层磁赤铁矿纳米粒子的制备,表征

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摘要

To report a modified preparation and to systematically study the structure, magnetic and other properties of γ-Fe2O3-DMSA-DG NPs (2-deoxy-D-glucose (2-DG) conjugated meso-2,3-dimercaptosuccinic acid coated γ-Fe2O3 nanoparticles) and test its ability to improve Hela tumor cells targeting in vitro compared to the γ-Fe2O3-DMSA NPs.
机译:报告改进的制备方法,并系统地研究γ-Fe2 O3 -DMSA-DG NPs(2-脱氧-D-葡萄糖(2-DG)共轭介孔- 2,3-二巯基琥珀酸包覆的γ-Fe2 O3 纳米颗粒)并测试其与γ-Fe2 O3 -DMSA相比对体外靶向Hela肿瘤细胞的改善能力NP。

著录项

  • 来源
    《Pharmaceutical Research》 |2012年第4期|p.1087-1097|共11页
  • 作者单位

    State Key Laboratory of Bioelectronics Jiangsu Laboratory for Biomaterials and Devices School of Biological Science &amp Medical Engineering, Southeast University, 2 Sipailou, Nanjing, China;

    State Key Laboratory of Bioelectronics Jiangsu Laboratory for Biomaterials and Devices School of Biological Science &amp Medical Engineering, Southeast University, 2 Sipailou, Nanjing, China;

    Department of Pharmacology, School of Basic Medicine, Hebei Medical University, Shijiazhuang, China;

    State Key Laboratory of Bioelectronics Jiangsu Laboratory for Biomaterials and Devices School of Biological Science &amp Medical Engineering, Southeast University, 2 Sipailou, Nanjing, China;

    Department of Radiology The Affiliated Renmin Hospital, Jiangsu University, Zhenjiang, China;

    State Key Laboratory of Bioelectronics Jiangsu Laboratory for Biomaterials and Devices School of Biological Science &a;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    2-deoxy-D-glucose; hela cells; iron oxide nanoparticles;

    机译:2-脱氧-D-葡萄糖;Hela细胞;氧化铁纳米粒子;

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