Low-Molecular-Weight Methylcellulose-Based Thermo-reversible Gel/Pluronic Micelle Combination System for Local and Sustained Docetaxel Delivery

Jang Kyoung Kim; Young-Wook Won; Kwang Suk Lim; Yong-Hee Kim

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Low-Molecular-Weight Methylcellulose-Based Thermo-reversible Gel/Pluronic Micelle Combination System for Local and Sustained Docetaxel Delivery

机译：基于低分子量甲基纤维素的热可逆凝胶/普流子胶束组合系统，用于局部和持续的多西他赛给药

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摘要

To develop low-molecular-weight methylcellulose (LMw MC)-based gel/Pluronic F127 micelle combination system for local and sustained delivery of docetaxel (DTX).

机译：开发低分子量甲基纤维素（LMw MC）基凝胶/ Pluronic F127胶束组合系统，用于多西他赛（DTX）的局部和持续递送。

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来源
《Pharmaceutical Research》 |2012年第2期|p.525-534|共10页
作者
Jang Kyoung Kim; Young-Wook Won; Kwang Suk Lim; Yong-Hee Kim;
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作者单位

Department of Bioengineering, Institute for Bioengineering &amp Biopharmaceutical Research Hanyang University, 17, Haengdang-dong, Seongdong-gu, Seoul, 133-791, Republic of Korea;

Department of Bioengineering, Institute for Bioengineering &amp Biopharmaceutical Research Hanyang University, 17, Haengdang-dong, Seongdong-gu, Seoul, 133-791, Republic of Korea;

Department of Bioengineering, Institute for Bioengineering &amp Biopharmaceutical Research Hanyang University, 17, Haengdang-dong, Seongdong-gu, Seoul, 133-791, Republic of Korea;

Department of Bioengineering, Institute for Bioengineering &amp Biopharmaceutical Research Hanyang University, 17, Haengdang-dong, Seongdong-gu, Seoul, 133-791, Republic of Korea;

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正文语种 eng
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关键词
cancer therapy; docetaxel; drug delivery; gel/micelle combination system; methylcellulose;

机译：癌症治疗;多西他赛;药物递送;凝胶/胶束联合系统;甲基纤维素;

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专利

1. Low-molecular-weight methylcellulose-based thermo-reversible gel/pluronic micelle combination system for local and sustained docetaxel delivery. [J] . Jang Kyoung Kim, Young-Wook Won, Kwang Suk Lim, Pharmaceutical research . 2012,第2期

机译：低分子量甲基纤维素基热可逆凝胶/普朗尼克胶束组合系统，用于局部和持续的多西他赛给药。
2. Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer [J] . Chia-En Chang, Chien-Ming Hsieh, Ling-Chun Chen, Drug delivery. . 2018,第1期

机译：普鲁尼克卵磷脂有机凝胶（PLOs）在多西他赛与顺铂协同组合中局部递送以提高抗卵巢癌疗效的新应用
3. Effect of salts on gelation and drug release profiles of methylcellulose-based ophthalmic thermo-reversible in situ gels. [J] . Manas Bhowmik, Mrinal Kanti Bain, Lakshmi Kanta Ghosh, Pharmaceutical development and technology . 2011,第4期

机译：盐对甲基纤维素基眼科热可逆原位凝胶的凝胶化和药物释放曲线的影响。
4. The combination of pluronic f 127 and pluronic f 68 - a new perspective for thermogelling drug delivery formulations [C] . F. Ruchatz, S. Lang, H. Reich, . 1998

机译：pluronic f 127和pluronic f 68的组合-热凝胶给药配方的新视角
5. A combined reverse thermal gel-polymeric micelle system for sustained delivery of ophthalmic drugs. [D] . Famili, Amin. 2014

机译：组合式逆向热凝胶-聚合物胶束系统，用于持续输送眼科药物。
6. Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer [O] . Chia-En Chang, Chien-Ming Hsieh, Ling-Chun Chen, 2018

机译：普鲁尼克卵磷脂有机凝胶在多西他赛与顺铂协同联合局部递送以提高抗卵巢癌疗效方面的新应用
7. Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer [O] . Chia-En Chang, Chien-Ming Hsieh, Ling-Chun Chen, 2018

机译：Pluronic卵磷脂有机凝胶（PLOS）对多西紫杉醇和顺铂协同组合的新应用，提高卵巢癌治疗疗效
8. In Vitro Evaluation of an Injectable Chitosan Gel for Sustained Local Delivery of BMP-2 for Osteoblastic Differentiation. [R] . Kim, S., Tsao, H., Kang, Y., 2011

机译：体外评价可注射的壳聚糖凝胶持续局部递送Bmp-2成骨细胞分化。

Low-Molecular-Weight Methylcellulose-Based Thermo-reversible Gel/Pluronic Micelle Combination System for Local and Sustained Docetaxel Delivery

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