Synthesis of Conformationally Constrained C-Glycosyl alpha-and beta-Amino Acids and Sugar-Carbamino Sugar Hybrids via Diels Alder Reaction

摘要

Sugar-derived dienes undergo Diels-Alder reactions with methyl alpha-nitro acrylate and ethyl beta-nitro acrylate to form the corresponding cycloadducts which have been converted into conformationally constrained C-glycosyl alpha-and beta-amino acids.Further,these beta-amino acids are converted into sugar-carbamino sugar hybrid molecules.