Copper(Ⅱ)-catalyzed highly regio- and stereo-selective hydrosilylation of unactivated internal alkynes with silylborate in water

摘要

The highly regio- and stereoselective hydrosilylation of internal alkynes with silylborate catalyzed by Cu(OTf)_2 with 1,10-phenan-throline as the ligand in the presence of Cs_2CO_3 in water is developed. This protocol was applied efficiently in the aqueous synthesis of multi-substituted vinylsilanes.