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Stockout risk of production-inventory systems with compound Poisson demands

机译:具有复合泊松需求的生产库存系统的缺货风险

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Production-inventory systems with continuous production or continuous manufacturing have been implemented in a variety of manufacturing contexts. Most recently, the Commissioner of the FDA has called on drug and biological product manufacturers to begin switching from batch manufacturing processes to continuous production. Motivated by prevailing applications and the emerging and promising landscape in the healthcare and pharmaceutical industries, this paper studies a continuous-review production-inventory system with a constant production rate and compound Poisson demands, in which the cost of the system is assessed via inventory holding, stockout penalty and production costs. For any initial inventory, we derive a closed-form expression for the expected discounted cost function until stockout occurrence. We systemically quantify the stockout risk on four different dimensions (i.e.,time, volume, frequencyandpercentage) and derive explicit expressions for each type of risk metric. The objective is to derive the production rate that minimizes the expected discounted system cost subject to a given risk tolerance level on stockouts. With the aid of the derived explicit forms of stockout risk and the cost function, we develop a computationally-efficient algorithm for the optimal solution. Extensive numerical studies are conducted to illustrate our results with rich insights. Numerically, we show that it is outrageously costly to reduce stockout risk, especially when this risk is relatively low; the value of risk is more sensitive to the stockout risk level if the demand distribution has a higher volatility.
机译:具有连续生产或连续制造的生产库存系统已在各种制造环境中实现。最近,FDA局长呼吁药品和生物制品制造商开始从批量生产过程转换为连续生产过程。受卫生保健和制药行业普遍应用和新兴前景看好的影响,本文研究了具有恒定生产率和复合泊松需求的连续审查生产库存系统,该系统的成本通过库存持有来评估,缺货罚款和生产成本。对于任何初始库存,我们推导出预期折现成本函数的封闭式表达式,直到出现缺货为止。我们系统地在四个不同维度(即时间,数量,频率和百分比)上对缺货风险进行量化,并为每种类型的风险指标导出明确的表达方式。目的是在给定的缺货风险容忍度水平下,得出使预期的折扣系统成本最小化的生产率。借助派生的缺货风险和成本函数的显式形式,我们为最优解决方案开发了一种计算有效的算法。进行了广泛的数值研究,以丰富的见解来说明我们的结果。从数值上看,我们发现降低缺货风险的代价非常高,尤其是当这种风险相对较低时;如果需求分布具有较高的波动性,则风险价值对缺货风险水平更为敏感。

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