Reproducibility evaluation of Tc-99m-mebrofenin hepatobiliary scintigraphy using SPECT for future remnant liver functional assessment before major hepatectomy

摘要

Purpose. - Performances of Tc-99m-mebrofenin hepatobiliary scintigraphy (BIBS) are currently evaluated before major hepatic resection for early detection of liver failure in high risk patients. Published studies included small numbers of patients with planar scintigraphy, and more recently SPECT data. Our aim was to evaluate intra- and interobserver reproducibility of HBS in planar and SPECT modalities for functional assessment of the future remnant liver (FRL) before major hepatic resection. We also evaluated the impact of potential variability factors such as biliary excretion and isocontour threshold choice.