Where protection against Alzheimer's is concerned, you can have too much of a good thing. If you inherit one copy of a particular gene mutation it seems to protect you from Alzheimer's. With a copy from each parent, you may be in trouble. Fabrizio Tagliavini of the Carlo Besta National Neurological Institute in Milan, Italy, and colleagues discovered the mutation in a 44-year-old man with signs of early-onset Alzheimer's who didn't have the usual gene mutations.
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