Dynamic platforms

摘要

Living cells are dynamic machines. They contain thousands of different proteins that participate in a maze of signalling pathways, all of which must be accurately organized in space and time for efficient cellular functioning. To achieve this level of organization, one strategy that cells use involves scaffolding proteins, which assemble proteins of a particular signalling pathway into multimolecular complexes, thereby promoting signalling specificity and speed while avoiding spurious crosstalk with other pathways.