A new generation of sequencing machines is broadening horizons for users. Various groups have recently performed epigenetic studies - looking at modifications to the genome that control its expression - that would have been utterly impractical using old technologies.rnThe latest approach fishes out all the DNA associated with a given marker, such as one of the histone proteins used to package genes in chromosomes. Then, instead of comparing each piece of DNA with a library of previously isolated sequences, as used to be done, scientists simply sequence the whole lot.
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