Imperfect yet striking

摘要

Noggle and colleagues' study is noteworthy for generating the first - albeit genetically abnormal - human pluripotent stem cells through oocyte-mediated reprogram-ming and for highlighting major technical barriers to SCNT using human eggs. Since the first isolation of human embryonic stem (ES) cells in 1998, a compelling strategy for the future envisaged exploiting SCNT to generate personalized embryonic stem cells.