Keep 'reproducibility' in context

摘要

The call by Glenn Begley and Lee Ellis to raise standards in preclinical cancer research (Narwre483,531-533; 2012) is an admirable piece of self-critique that can be extended to all who study and treat human disease. Unfortunately, the kernel of their polemic - that reproducing published results can be problematic - was widely misinterpreted by the media.The authors highlight an investigation in which scientific findings were confirmed in only 6 of 53 cases.