Onconova Therapeutics, Inc.

摘要

Onconova Therapeutics, Inc., based in Newtown PA, USA, is a clinical-stage biophar-maceutical company focused on discovering and developing novel small molecule drug candidates to treat cancer. Myelodysplastic Syndromes Myelodysplastic syndromes (MDS) are a group of blood disorders that affect bone marrow function. In MDS, bone marrow becomes dysplastic, or defective, and produces an inadequate supply of blood cells that do not develop normally, leading to cyto-penias. In most cases, the disease worsens (Fig. 1) and the patient develops progressive bone marrow failure, often leading to acute myelogenous leukemia (AML).