Evaluation of Tracer Kinetic Models for Analysis of [18F]FDDNP Studies

Maqsood Yaqub; Ronald Boellaard; Bart N. M. van Berckel; Nelleke Tolboom; Gert Luurtsema; Anke A. Dijkstra; Mark Lubberink; Albert D. Windhorst; Philip Scheltens; Adriaan A. Lammertsma

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Evaluation of Tracer Kinetic Models for Analysis of [18F]FDDNP Studies

机译：用于[18 F] FDDNP研究的示踪动力学模型的评估

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摘要

Different pharmacokinetic methods for [18F]FDDNP studies were evaluated using both simulations and clinical data.

机译：使用模拟和临床数据评估了[18 F] FDDNP研究的不同药代动力学方法。

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来源
《Molecular Imaging and Biology》 |2009年第5期|322-333|共12页
作者
Maqsood Yaqub; Ronald Boellaard; Bart N. M. van Berckel; Nelleke Tolboom; Gert Luurtsema; Anke A. Dijkstra; Mark Lubberink; Albert D. Windhorst; Philip Scheltens; Adriaan A. Lammertsma;
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作者单位

Department of Nuclear Medicine ampamp PET Research VU University Medical Centre P.O. Box 7057 1007 MB Amsterdam The Netherlands;

Department of Nuclear Medicine ampamp PET Research VU University Medical Centre P.O. Box 7057 1007 MB Amsterdam The Netherlands;

Department of Nuclear Medicine ampamp PET Research VU University Medical Centre P.O. Box 7057 1007 MB Amsterdam The Netherlands;

Department of Neurology ampamp Alzheimer Centre VU University Medical Centre P.O. Box 7057 1007 MB Amsterdam The Netherlands;

Department of Nuclear Medicine ampamp PET Research VU University Medical Centre P.O. Box 7057 1007 MB Amsterdam The Netherlands;

Department of Nuclear Medicine ampamp PET Research VU University Medical Centre P.O. Box 7057 1007 MB Amsterdam The Netherlands;

Department of Nuclear Medicine ampamp PET Research VU University Medical Centre P.O. Box 7057 1007 MB Amsterdam The Netherlands;

Department of Nuclear Medicine ampamp PET Research VU University Medical Centre P.O. Box 7057 1007 MB Amsterdam The Netherlands;

Department of Neurology ampamp Alzheimer Centre VU University Medical Centre P.O. Box 7057 1007 MB Amsterdam The Netherlands;

Department of Nuclear Medicine ampamp PET Research VU University Medical Centre P.O. Box 7057 1007 MB Amsterdam The Netherlands;

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原文格式 PDF
正文语种 eng
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关键词
18FFDDNP; PET; SUV; Reference tissue model; Plasma input model; Metabolites;

机译：[18F] FDDNP;PET;SUV;参考组织模型;等离子输入模型;代谢产物;

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专利

1. Evaluation of tracer kinetic models for analysis of (18F)FDDNP studies. [J] . Yaqub M, Boellaard R, van Berckel BN Molecular imaging and biology: MIB : the official publication of the Academy of Molecular Imaging . 2009,第5期

机译：评估示踪动力学模型以分析（18F）FDDNP研究。
2. PET/CT studies of multiple myeloma using 18F-FDG and 18F-NaF: Comparison of distribution patterns and tracers' pharmacokinetics [J] . SachpekidisC., GoldschmidtH., HoseD., European Journal of Nuclear Medicine and Molecular Imaging . 2014,第7期

机译：使用18F-FDG和18F-NaF进行多发性骨髓瘤的PET / CT研究：分布模式和示踪剂药代动力学的比较
3. PET/CT studies of multiple myeloma using 18F-FDG and 18F-NaF: Comparison of distribution patterns and tracers' pharmacokinetics [J] . SachpekidisC., GoldschmidtH., HoseD., European Journal of Nuclear Medicine and Molecular Imaging . 2014,第7期

机译：使用18F-FDG和18F-NaF进行多发性骨髓瘤的PET / CT研究：分布模式和示踪剂药代动力学的比较
4. Kinetic analysis of dynamic 18F-FDG and 15O-H2O PET studies by parametric and nonparametric methods: A statistical analysis [C] . Hernandez Fernandez Francisco, Hawe David, OSuilleabhain Liam, IEEE Nuclear Science Symposium and Medical Imaging Conference . 2011

机译：动态 18 f-f-f-f-f-f-f-f-h 15 O-h 2 O PET研究的动力学分析：参数和非参数方法：统计分析
5. An evaluation of radiogenic isotopes as tracers of ocean circulation and sediment transport: modeling, seawater, and sediment studies. [D] . Jones, Kevin Michael. 2010

机译：评估放射性同位素作为海洋环流和沉积物迁移的示踪剂：建模，海水和沉积物研究。
6. Evaluation of Tracer Kinetic Models for Analysis of 18FFDDNP Studies [O] . Maqsood Yaqub, Ronald Boellaard, Bart N. M. van Berckel, -1

机译：用于18F FDDNP研究分析的示踪动力学模型的评估
7. Evaluation of Tracer Kinetic Models for Analysis of [18F]FDDNP Studies [O] . Yaqub, Maqsood, Boellaard, Ronald, van Berckel, Bart N. M., 2009

机译：用于[18F] FDDNP研究分析的示踪动力学模型的评估

Evaluation of Tracer Kinetic Models for Analysis of [18F]FDDNP Studies

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