Hepatic cytochrome P450 IA and 7-ethoxyresorufin O-deetliylase induction in mullet and common sole as an indicator of toxic organic pollution in lzmir Bay, Turkey

摘要

In this study, the degree of induction of cytochrome P4501A-associated 7-ethoxyresorufin O-deethylase (EROD) activity and immunochemical detection of cytochrome P450lA in leaping mullet (Liza saliens) and common sole (Solea vulgaris) were used as biomarker for assessment of polycyclic aromatic hydrocarbon (PAH) or/and polychlorinated biphenyl (PCB) type organic pollutants along the lzmir Bay on the Aegean Sea coast, Turkey. Fish were captured in May 1995 and February and June 1996. Mullet caught from Pasaport, a highly urbanized and industrial section of the Bay, had approximately 62 times more EROD activity than the feral fish sampled from an uncontaminated site in the Outer Bay.