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首页> 外文期刊>The Journals of Gerontology Series A: Biological Sciences and Medical Sciences >Association Between Functional Polymorphisms of Renin-Angiotensin System, Left Ventricular Mass, and Geometry Over 4 Years in a Healthy Chinese Population Aged 60 Years and Older
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Association Between Functional Polymorphisms of Renin-Angiotensin System, Left Ventricular Mass, and Geometry Over 4 Years in a Healthy Chinese Population Aged 60 Years and Older

机译:60岁以上健康中国人群肾素-血管紧张素系统功能多态性,左心室质量与4年以上几何之间的关联

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摘要

Background. Cross-sectional studies investigated the impact of renin-angiotensin system (RAS) gene polymorphism on left ventricular mass index (LVMI) with conflicting results. We conducted a longitudinal study to investigate the influence of the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) and angiotensinogen (AGT) M235T and angiotensin II type 1 receptor (AT1R) A1166C gene polymorphisms on the LVMI and geometry.
机译:背景。横断面研究调查了肾素-血管紧张素系统(RAS)基因多态性对左心室质量指数(LVMI)的影响,但结果相互矛盾。我们进行了一项纵向研究,以研究血管紧张素转换酶(ACE)插入/缺失(I / D)和血管紧张素原(AGT)M235T和血管紧张素II 1型受体(AT1R)A1166C基因多态性对LVMI和几何形状的影响。

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