The quantitative measurement of BCL-2, P53 protein and PCNA expression in breast carcinoma and their correlation with prognosis

摘要

To study quantitative index of bcl-2, P53, proliferating cell nuclear antigen(PCNA), ER and PR in breast carcinoma and their correlation and their relationship with prognosis, the ex- Pression of bcl-2, P53 and PCNA were studied by immunohistochemical technique. The measurement Of ER and PR used enzyme linked affinity histochemical methods. The quantitative index was ana- Lyzed by image technique. All analyses were based on 60 breast carcinomas. The results were as fol- Lows: the more bcl-2 protein, the lower histological grade; the longer survival term and the higher Survival rate(P < 0.05).