Stereochemical Course of Malonate Decarboxylation in Malonomonas rubra

摘要

The above results demonstrate that the malonate decarboxylase of M. rubra decarboxylates malonate with retention of configuration. This agrees with the stereochemistry observed for all other biotin-containing decarboxylases, most of which act on CoA esters rather than on the free acids. It suggests that the M. rubra malonate decarboxylase may operate by a similar mechanism.