Cooperativity in Chiroptical Sensing with Dendritic Zinc Porphyrins

摘要

Dendrimers are regularly branched three-dimensional macro-molecules,whose properties are dependent on the numbers of generation and branch units,along with the structures of building blocks,surface groups,and core modules.Site-selective positioning of functional groups in dendritic architectures is expected to induce cooperative phenomena that may lead to a significant enhancement of certain functions.Examples of such cooperative phenomena with dendritic macromolecules have been reported for catalysis,molecular recognition and inclusion,and light harvesting.We are motivated to explore the potential utility of such a cooperative phenomenon for sensory applications.Here,we report the synthesis of a series of dendritic macromolecules functionalized with multiple zinc porphyrin units (Chart 1) and highlight a clear cooperative effect on chiroptical sensing of an asymmetric ligating molecule.