Room-Temperature Catalytic Hydrodefluorination of C(sp~3)-F Bonds

摘要

Activation of carbon-fluorine bonds remains one of the major challenges of modern organometallic chemistry.C-F activation is both a fundamentally appealing task(C-F is the strongest single bond to carbon)and one of practical relevance to the potential remediation of atmospheric pollutants.Freons(CFCs)are a proven hazard to the ozone layer,while CF4 and heavier perfluoroalkanes are extremely potent and long-lived greenhouse gases.The simplest transformation of a C-F bond is conversion to a C-H bond(hydrodefluorination or HDF,eqs 1 and 2).