Halogenation of Unactivated Carbon Centers in Natural Product Biosynthesis:Trichlorination of Leucine during Barbamide Biosynthesis

Danica P.Galonic; Frederic H.Vaillancourt; Christopher T.Walsh

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Halogenation of Unactivated Carbon Centers in Natural Product Biosynthesis:Trichlorination of Leucine during Barbamide Biosynthesis

机译：天然产物生物合成中未活化碳中心的卤化：Barbamide生物合成过程中亮氨酸的三氯化

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Halogenation is a common structural feature of more than 4500 natural products of both marine and terrestrial origin.This biosynthetic modification has a profound influence on the biological activity of the resulting compounds.

机译：卤化是超过4500种海洋和陆生天然产物的常见结构特征，这种生物合成修饰对所得化合物的生物活性产生深远影响。

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《Journal of the American Chemical Society》 |2006年第12期|p.3900-3901|共2页
作者
Danica P.Galonic; Frederic H.Vaillancourt; Christopher T.Walsh;
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作者单位

Department of Biological Chemistry and Molecular Pharmacology,Harvard Medical School,Boston,Massachusetts 02115;

Department of Biological Chemistry and Molecular Pharmacology,Harvard Medical School,Boston,Massachusetts 02115;

Department of Biological Chemistry and Molecular Pharmacology,Harvard Medical School,Boston,Massachusetts 02115;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类化学;
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入库时间 2022-08-18 03:22:33

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专利

1. Halogenation strategies in natural product biosynthesis [J] . Neumann CS, Fujimori DG, Walsh CT Chemistry & biology . 2008,第2期

机译：天然产物生物合成中的卤化策略
2. Cylindrocyclophane Biosynthesis Involves Functionalization of an Unactivated Carbon Center [J] . Hitomi Nakamura, Hilary A Hamer, Gopal Sirasani, Journal of the American Chemical Society . 2012,第45期

机译：Cylindrocyclophane生物合成涉及未激活的碳中心的功能化。
3. Biosynthesis of novel carotenoid families based on unnatural carbon backbones: A model for diversification of natural product pathways [J] . Tobias AV, Arnold FH Biochimica et Biophysica Acta. Molecular and cell biology of Lipids . 2006,第2期

机译：基于非天然碳主链的新型类胡萝卜素家族的生物合成：天然产物途径多样化的模型
4. Benchmarking Evolutionary Algorithms on Convenience Kinetics Models of the Valine and Leucine Biosynthesis in C. glutamicum [C] . Andreas Drager, Marcel Kronfeld, Jochen Supper, IEEE Congress on Evolutionary Computation . 2007

机译：基于C.谷氨酰胺的缬氨酸和亮氨酸生物合成的便利动力学模型的基准进化算法
5. Enzymatic halogenation during natural product biosynthesis. [D] . Yeh, Ellen. 2006

机译：天然产物生物合成过程中的酶促卤化反应。
6. Cylindrocyclophane Biosynthesis Involves Functionalization of an Unactivated Carbon Center [O] . Hitomi Nakamura, Hilary A. Hamer, Gopal Sirasani, -1

机译：Cylindrocyclophane生物合成涉及未激活的碳中心的功能化
7. Halogenation of Unactivated Carbon Centers in Natural Product Biosynthesis: Trichlorination of Leucine during Barbamide Biosynthesis [O] . -1

机译：天然产物生物合成中未激活的碳中心的卤化：氨基甲酰胺生物合成期间亮氨酸三氯化

Halogenation of Unactivated Carbon Centers in Natural Product Biosynthesis:Trichlorination of Leucine during Barbamide Biosynthesis

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