Cationic Rhodium(l)— dppf Complex-Catalyzed Olefin Isomerization/Propargyl Claisen Rearrangement/Carbonyl Migration Cascade

摘要

Cascade reactions, which can eliminate a number of reaction steps and reduce hazardous waste, have attracted much attention in current organic synthesis. It is well-known that transition-metal complexes are able to activate σ bonds by oxidative addition of those bonds to the transition metal or by an electrophilic substitution pathway; π bonds can also be activated through the formation of a complex between an electrophilic transition metal and the π electrons of alkene or alkyne multiple bonds.