Graphene-Based SELDl Probe with Ultrahigh Extraction and Sensitivity for DNA Oligomer

摘要

We demonstrate that graphene can be used as an ultrahigh efficiency preconcentration and detection platform for ssDNA. DNA-adsorbed graphene can be used directly for Surface Enhanced Laser Desorption lonization-Time of Flight-Mass Spec-trometry (SELDl-TOF-MS). The rapid enrichment of biomolecules and direct, label-free detection are potentially useful for analysis in proteomics and genomics.