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The differently expressed proteins in MSCs of degenerative scoliosis

机译:变性脊柱侧凸间充质干细胞中表达差异的蛋白质

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摘要

Purpose Degenerative scoliosis (DS) is an important degenerative lumbar disease causing spinal dysfunction. The true reason or pathogenesis of DS is still unknown. Bone marrow-derived mesenchymal stem cells (BM-MSCs) are the stem/progenitor cells of the osteoblasts. The diseases associated with osteogenesis could be caused by abnormality of the MSCs. The purpose of this study was to find the differential proteins expressed in MSCs of patients with DS.
机译:目的退行性脊柱侧凸(DS)是一种重要的退行性腰椎疾病,引起脊柱功能障碍。 DS的真正原因或发病机理仍然未知。骨髓来源的间充质干细胞(BM-MSC)是成骨细胞的干/祖细胞。与成骨相关的疾病可能是由于MSC异常引起的。这项研究的目的是发现在DS患者的MSC中表达的差异蛋白。

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  • 来源
    《Journal of Orthopaedic Science》 |2013年第6期|885-892|共8页
  • 作者单位

    Department of Orthopaedics Provincial Hospital Affiliated to Shandong University">(1);

    Department of Orthopaedics The First Affiliated Hospital Of Chongqing Medical University">(2);

    Department of Orthopedic Surgery Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College">(3);

    Department of Orthopedic Surgery Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College">(3);

    Department of Orthopedic Surgery Peking Union Medical College Hospital Chinese Academy of Medical Science and Peking Union Medical College">(3);

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