Chelation-assisted intermolecular hydroacylation: direct synthesis of ketone from aldehyde and 1-alkene

摘要

Activation of the aldehydic carbon-hydrogen bond by transition-metal complexes has especially received inter- est because of its relevance to organic synthesis through conversion of aldehyde into ketone (i.e., hydroacylation). A negative consequence in the synthesis of ketone from Aldehyde is decarbonylation in the acylmental intemedi- Ate, formed by cleavage of the aldehydic carbon- Hydrogen bond.