Suzuki?Miyaura Coupling of Aryl Iodides, Bromides, and Chlorides Catalyzed by Bis(thiazole) Pincer Palladium Complexes

摘要

Bis(thiazole) pincer palladium complexes showednefficient catalytic activity for the Suzuki−Miyaura coupling of arylnhalides, allowing the synthesis of biaryls with very high turnovernnumbers and turnover frequencies. The complexes werensuccessfully applied in the scalable and green synthesis of thenkey intermediates of bioactive LUF5771 and its analogues.