Formation of Acridones by Ethylene Extrusion in the Reaction of Arynes with β-Lactams and Dihydroquinolinones

摘要

N-Unsubstituted β-lactams react with a moleculenof aryne by insertion into the amide bond to form a 2,3-ndihydroquinolin-4-one, which subsequently reacts with anothernmolecule of aryne to form an acridone by extrusion of anmolecule of ethylene. 2,3-Dihydroquinolin-4-ones react undernthe same reaction conditions to afford identical results. This isnthe first example of ethylene extrusion in aryne chemistry.