LARGE SCALE PRODUCTION OF OCTYL-9,10-DIHYDROXYSTEARATE BY IMMOBILIZED LIPASE

摘要

Large scale production of octyl-9,10-dihydroxystearate was performed in a 5-litre batch, stirred tank reactor with a multi-bladed propeller. The effects of reaction temperature, reaction time, enzyme dosage and agitation speed were studied. The optimal conditions for the ester synthesis were reaction temperature at 50℃, reaction time of 3 hr, catalyst concentration of 10% (w/w) and agitation speed of 300 rpm. The percentage conversion was about 90% with respect to the amount of dihydroxystearic acid (DHSA) used. The operational stability of the catalyst was also evaluated.