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Focused Ultrasound Ablation for the Treatment of Patients With Localized Deformed Breast Cancer: Computer Simulation

机译:聚焦超声消融治疗局部变形性乳腺癌的患者:计算机模拟

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摘要

This paper is carried out on the computer simulation of breast cancer treated using a high intensity focused ultrasound (HIFU). The mathematical models consist of the pressure acoustics equation, bioheat equation, heat transfer in a blood vessel, momentum equations in a blood vessel, and mechanical deformation equation. In the numerical simulation, these mathematical models are solved by using an axisymmetric finite element method (FEM) with time-dependent, thermal and acoustic properties to describe the temperature distribution and the total displacement in tissue. The comparison of the simulated results in the model with two sizes of the cancer tumor and two frequencies of ultrasound are also considered in order to approach realistic tissue modeling. The results show that the breast cancer model with deformation, which is the more accurate way to simulate the physical characteristics of therapeutic breast cancer compared to the literature results, hence leads to more useful in the medical approach and this study was conducted to prevent errors caused by inaccurate focal points.
机译:本文是在使用高强度聚焦超声(HIFU)治疗的乳腺癌的计算机模拟上进行的。数学模型由压力声学方程,生物热方程,血管中的热传递,血管中的动量方程和机械变形方程组成。在数值模拟中,这些数学模型通过使用轴对称有限元方法(FEM)求解,该方法具有随时间变化的热和声学特性,以描述组织中的温度分布和总位移。为了接近现实的组织建模,还考虑了具有两种尺寸的癌肿瘤和两种超声频率的模型中模拟结果的比较。结果表明,与文献结果相比,具有变形的乳腺癌模型是更准确地模拟治疗性乳腺癌的物理特征的方法,因此在医学方法中具有更大的实用性,并且本研究旨在防止引起的错误通过不正确的焦点。

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