Directly assembled electrochemical sensor by combining self-supported CoN nanoarray platform grown on carbon cloth with molecularly imprinted polymers for the detection of Tylosin

摘要

Molecularly imprinted polymers (MIPs) based on electrochemical sensors (MIP-EC sensors) have obtained ideal achievements in recent years. However, some challenges are still need to be addressed, such as adjustable preparation, unstable sensing interface and great signal-to-noise ratio. Here, based on the ingenious combination of the MIP and the self-supported CoN nanowire arrays grown on carbon cloth (CoN NWs/CC), a robust MIP-EC sensor was developed, in which the MIP film was uniformly coated on the CoN NWs/CC via a bulk polymerization crosslinking process. Especially, CoN NWs/CC were prepared via in-situ transformation of their oxide precursors and then directly as a candidate of EC electrode. Under the optimal conditions, the MIP-EC sensor can detect Tylosin (TS) in the concentration range from 8.6 x 10(-11) to 6.7 x 10(-5) mol L-1, and the low detection limit (LOD) is 5.5 x 10(-12) mol L-1 (S/N = 3). Furthermore, the MIP-EC sensor showed high selectivity, reproducibility and stability. The practicability of the MIP-EC sensor was tested in the actual samples of surface water and soil with the comparison of the traditional ELISA method. The developed MIP-EC sensor with simple and fabrication process can provide a versatile and reliable method, which has great potential application value for the detection of small hazardous molecules.