Inhibition of Oxidative and Antioxidative Enzymes by Trans-Resveratrol

摘要

Trans-resveratol, a phytoalexin produced by a variety of plants, has been shown to inhibit oxidative enzymes in an animal cell system. Its effect on several oxidative and antioxidative enzymes from plants was investigated using in vitro assays. Trans-resveratrol inhibited superoxide dismutase, lipoxygenase, catalase, peroxi- dase, polyphenol oxidase, and 1-aminocyclopropane-1-carboxylic acid oxidase with apparent K_1's of 10 , 90, 100, 255, 305, and 350 μm, respectively.