Adverse health effects of environmental chemical agents through non-genotoxic mechanisms

摘要

Over the past century, industrialisation in the western hemisphere led to the high-volume production of thousands of different chemicals and complex preparations and their release into the environment. These compounds can be separated into those that were synthesised and released intentionally and others that arose as by-products from various industrial processes. A subgroup among these chemicals are persistent in terms of environmental biodegradation and thus stay alive for a long time in the environment with the potential to emerge as contaminants in the food chain. Compounds produced on purpose include biocides, pesticides, flame retardants, plasticisers, preservatives and additives used in foods or cosmetics, and consumer products.