An excess of tetralogy of Fallot in Malta

摘要

Conclusions-The Maltese gene pool seems to have a genetic predisposition towards live births with TF. Population genetic studies with emphasis on the prevalence of 22q11 microdeletion may yield clues regarding the cause of the high rate of this condition. Study objective-To estimate birth preva- Lence of tetralogy of Fallot (TF) in Malta. Design-Retrospective data collection and Analysis, and comparison with earlier epi- Demiological studies dealing with on- Genital heart disease. Setting-Regional hospital providing ex- Clusive diagnostic and follow up services For the entire country of Malta.