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Major Advances in Genetic Evaluation Techniques

机译:遗传评价技术的重大进展

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The past quarter-century in genetic evaluation of dairy cattle has been marked by evolution in methodology and computer capacity, expansion in the array of evaluated traits, and globalization. Animal models replaced sire and sire-maternal grandsire models and, more recently, application of Bayesian theory has become standard. Individual test-day observations have been used more effectively in estimation of lactation yield or directly as input to evaluation models. Computer speed and storage are less limiting in choosing procedures. The increased capabilities have supported evaluation of additional traits that affect the net profitability of dairy cows. The importance of traits other than yield has increased, in a few cases due to an antagonistic relationship with yield. National evaluations combined internationally provide evaluations for bulls from all participating countries on each of the national scales, facilitating choices from among many more bulls. Selection within countries has increased inbreeding and the use of similar genetics across countries reduces the previously available outcross population. Concern about inbreeding has prompted changes in evaluation methodology and mating practices, and has promoted interest in crossbreeding. In just the past decade, distribution of genetic evaluations has gone from mailed paper or computer tapes for a limited audience to publicly accessible, request-driven distribution via the Internet. Among the distributed information is a choice of economic indices that combine an increasing array of traits into numbers reflecting breeding goals under different milk-pricing conditions. Considerable progress in genomics and the mapping of the bovine genome have identified markers for some deleterious recessive genes, but broader benefits of marker-assisted selection are still in the future. A possible exception is the proprietary use of DNA testing by semen producers to select among potential progeny test bulls. The collection and analysis of industry-wide data to evaluate ge- netic merit will continue to be the most important tool for genetic progress into the foreseeable future.
机译:在过去的25年中,奶牛的基因评估一直以方法论和计算机能力的发展,被评估性状的扩展以及全球化为标志。动物模型代替了父代和父代-祖代的孙代模型,最近,贝叶斯理论的应用已成为标准。各个试验日的观察结果已更有效地用于估计泌乳量或直接用作评估模型的输入。计算机速度和存储在选择过程中的限制较小。功能的增强支持评估影响奶牛净利润的其他特征。在某些情况下,由于与产量的拮抗关系,除产量以外的其他性状的重要性已经提高。国家评估结合了国际水平,可以在每个国家规模上对所有参与国的公牛进行评估,从而有助于从更多公牛中进行选择。在国家内进行选择增加了近亲繁殖,并且在国家间使用相似的遗传基因减少了以前可获得的异族种群。对近交的关注促使评估方法和交配实践发生了变化,并引起了人们对杂交的兴趣。在过去的十年中,遗传评估的分发已经从针对特定受众的邮寄纸质或计算机磁带,到通过互联网公开访问,由请求驱动的分发。在分发的信息中,有一些经济指标可供选择,这些指标将越来越多的性状组合成反映不同奶价条件下育种目标的数量。基因组学和牛基因组图谱的巨大进步已经确定了一些有害隐性基因的标记,但标记辅助选择的广泛益处仍在未来。可能的例外是精液生产者专有地使用DNA测试来选择潜在的后代测试公牛。收集和分析整个行业的数据以评估遗传优势,将继续是在可预见的将来遗传进步的最重要工具。

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