Homo- and hetero-dinuclear derivatives of aluminium containing Schiff-base ligands: synthesis, characterization and antibacterial activity of mononuclear derivative of aluminium

摘要

Reactions of Al(OPri)₃ with LH₂  = [R′C(NYOH)CHC(R)OH] R=R′=CH₃, Y  = (CH₂)₂ (L1H₂); R  = CH₃, R′  = C₆H₅, Y  = (CH₂)₂ (L2H₂); R  = R′  = CH₃, Y  = (CH₂)₃ (L3H₂); R  = CH₃, R′  = C₆H₅, Y  = (CH₂)₃ (L4H₂), in 1 : 2 molar ratio give mononuclear derivatives of aluminium AlLLH (1a-1d). Equimolar reactions of AlLLH with M(OPri)₃ (M  = Al and B) yield homo- and hetero-dinuclear derivatives AlLLM(OPri)₂ (M=Al=2a-2d M=B=3a-3d). Reaction of 2a with L1H₂ affords AlL1L1AlL1 (4). All these derivatives have been characterized by elemental analysis, molecular weight measurements and plausible structures have been suggested on the basis of IR, NMR [1H, 13C, 27Al and 11B] spectral data and FAB-mass studies of 2b and 3b. Schiff base L1H₂ and its mononuclear derivative with aluminium (AlL1L1H) have been screened for their antibacterial activity against Escherischia coli and Bacillus subtilis.View full textDownload full textKeywordsSchiff-base ligand, Penta and tetracoordinated aluminium, Tetracoordinate boron, 11B and 27Al NMR studiesRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/00958970701615847