Evidence of type II pneumocyte apoptosis in the pathogenesis of idiopathic pulmonary fibrosis (IFP)/usual interstitial pneumonia (UIP)

摘要

Background/Aims-The pathogenesis of idiopathic pulmonary fibrosis (IPF)/usual interstitial penumonia (UIP), a chronic and incurable human respiratory disease, is not well established. This study was designed to investigate whether the apop- tosis of type II pneumocytes could be the precipitating factor in the pathogenesis of IPF.