Intestinal immune cells in Strongyloides stercoralis infection

摘要

Conclusions-Compared with seven healthy uninfected volunteers, a group of 19 Brazilians with clinically mild strongy- loides infection showed no abnormality of mucosal structure and no increase in non- specific inflammatory cells. Likewise, there was no increase in mucosal T cells or macrophages. Background-Strongyloides stercoralis Can cause a wide spectrum of disease in Man, ranging from a chronic asympto- Matic infection to a hyperinfective, often Fatal syndrome. In rodents, spontaneous Expulsion of Strongyloides spp occurs After experimental infection. Mast cells, Goblet cells, and eosinophils have been Identified as possible effectors of this Expulsion.