Flow cytometric DNA hypertetraploidy is associated with unfavourable prognostic features in breast cancer

摘要

Conclusion-Flow cytometric DNA hy- pertetraploidy is related to clinicopatho- logical features of breast cancer usually associated with unfavourable prognosis. Aim-Breast tumours with a DNA content Higher than 4N (hypertetraploidy) are not Well characterised. The aim of this study Was to evaluate the clinical and biological Characteristics of 51 hypertetraploid Breast carcinomas selected from a series Of 860 consecutive cases analysed by flow Cytometry. Methods-The clinicopathological char- Acteristics of the hypertetraploid group Were compared with those of a control Group of 138 non-hypertetraploid breast Carcinomas.