Cerebrospinal fluid plasminogen activator inhibitor-1 in patients with neurological disease

摘要

Conclusions-Raised CSF PAI-1 concen- trations may be used as a non-specific marker of neurological disease. Moreover, PAI-1 may play an important role in regu- Lating the functions of tPA, and probably UPa, in CSF. Aim-To study cerebrospinal fluid (CSF) Concentrations of plasminogen activator Inhibitor type-1 (PAI-1) in patients with Neurological disease. Methods-CSF PAI-1 concentrations were Measured in 51 patients with neurological Disease and 20 reference subjects using an ELISA.