Lymphoma associated bone marrow necrosis with raised anticardiolipin antibody

摘要

A case of high grade B cell lymphoma presented with bone marrow necrosis, fol- lowed by development of extensive mar- row fibrosis, the evolution of which was documented by serial magnetic resonance imaging and bone marrow trephine his- tology. A markedly raised anticardiolipin antibody titre at diagnosis suggests that lymphoma associated antiphospholipid syndrome may have contributed to the aetiology of the bone marrow necrosis.