Phase I clinical and pharmacological study of intraperitoneal cis-bis-neodecanoato(trans-R, R-1, 2-diaminocyclohexane)-platinum II entrapped in multilamellar liposome vesicles

C. F. Verschraegen; S. Kumagai; R. Davidson; B. Feig; P. Mansfield; S. J. Lee; D. S. Maclean; W. Hu; A. R. Khokhar; Z. H. Siddik

首页> 外文期刊>Journal of Cancer Research and Clinical Oncology >Phase I clinical and pharmacological study of intraperitoneal cis-bis-neodecanoato(trans-R, R-1, 2-diaminocyclohexane)-platinum II entrapped in multilamellar liposome vesicles

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Phase I clinical and pharmacological study of intraperitoneal cis-bis-neodecanoato(trans-R, R-1, 2-diaminocyclohexane)-platinum II entrapped in multilamellar liposome vesicles

机译：多层脂质体囊泡包埋的腹膜内顺式-双-新十二烷基（trans-R，R-1，2-二氨基环己烷）-铂II的I期临床和药理研究

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摘要

To perform a phase I study of intraperitoneal cis-bis-neodecanoato (trans-R, R-1, 2-diaminocyclohexane)-platinum II entrapped in multilamellar vesicles (L-NDDP) for peritoneal carcinomatosis or sarcomatosis.

机译：为了进行I期研究，腹膜内顺式-双-neodecanoato（反式-R，R-1、2-二氨基环己烷）-铂II包裹在多层囊泡（L-NDDP）中，用于腹膜癌变或肉瘤。

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来源
《Journal of Cancer Research and Clinical Oncology》 |2003年第10期|549-555|共7页
作者
C. F. Verschraegen; S. Kumagai; R. Davidson; B. Feig; P. Mansfield; S. J. Lee; D. S. Maclean; W. Hu; A. R. Khokhar; Z. H. Siddik;
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作者单位

University of New Mexico Cancer Research and Treatment CenterDepartment of Clinical Investigation The University of Texas M.D. Anderson Cancer Center;

Department of Clinical Investigation The University of Texas M.D. Anderson Cancer Center;

Departments of Surgical Oncology The University of Texas M.D. Anderson Cancer Center;

Departments of Surgical Oncology The University of Texas M.D. Anderson Cancer Center;

Departments of Surgical Oncology The University of Texas M.D. Anderson Cancer Center;

Department of Clinical Investigation The University of Texas M.D. Anderson Cancer Center;

Department of Clinical Investigation The University of Texas M.D. Anderson Cancer Center;

Department of Clinical Investigation The University of Texas M.D. Anderson Cancer Center;

Department of Clinical Investigation The University of Texas M.D. Anderson Cancer Center;

Department of Clinical Investigation The University of Texas M.D. Anderson Cancer Center;

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原文格式 PDF
正文语种 eng
中图分类
关键词
Laparoscopy; Peritoneal neoplasms; Organoplatinum compounds; Mesothelioma;

机译：腹腔镜;腹膜肿瘤;有机铂化合物;间皮瘤;

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外文文献

1. Phase I clinical and pharmacological study of intraperitoneal cis-bis-neodecanoato( trans- R, R-1, 2-diaminocyclohexane)-platinum II entrapped in multilamellar liposome vesicles. [J] . Verschraegen CF, Kumagai S, Davidson R, Journal of Cancer Research and Clinical Oncology . 2003,第10期

机译：多层脂质体囊泡中包埋的腹膜内顺式-双-neodecanoato（反式R，R-1、2-二氨基环己烷）-铂II的I期临床和药理研究。
2. Basic studies on gene therapy of human malignant melanoma by use of the human interferon gene entrapped in cationic multilamellar liposomes.: 1. Morphology and growth rate of six melanoma cell lines used in transfection experiments with the human interferon gene [J] . Gh. Benga Journal of cellular and molecular medicine. . 2001,第4期

机译：利用包裹在阳离子多层脂质体中的人干扰素基因对人恶性黑色素瘤进行基因治疗的基础研究：1.用人干扰素基因进行转染实验的六种黑色素瘤细胞系的形态和生长速率
3. A Phase I clinical and pharmacological study of cis-diamminedichloro(2-methylpyridine) platinum II (AMD473) [J] . P Beale, I Judson, A ODonnell, British Journal of Cancer . 2003,第7期

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6. Basic studies on gene therapy of human malignant melanoma by use of the human interferon β gene entrapped in cationic multilamellar liposomes.: 1. Morphology and growth rate of six melanoma cell lines used in transfection experiments with the human interferon β gene [O] . Gh. Benga 2001

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7. Basic studies on gene therapy of human malignant melanoma by use of the human interferon ? gene entrapped in cationic multilamellar liposomes.: 1. Morphology and growth rate of six melanoma cell lines used in transfection experiments with the human interferon ? gene [O] . Gh. Benga 2001

机译：使用人干扰素对人恶性黑素瘤基因治疗的基础研究？捕获阳离子多层脂质体的基因：1。与人干扰素转染实验的六黑色素瘤细胞系的形态和生长速率？基因
8. Fluorescence Depolarization Studies of the Phase Transition in Multilamellar Phospholipid Vesicles Exposed to 1.0-GHz Microwave Radiation [R] . Allis, J. W. , Sinha, B. L. 1982

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Phase I clinical and pharmacological study of intraperitoneal cis-bis-neodecanoato(trans-R, R-1, 2-diaminocyclohexane)-platinum II entrapped in multilamellar liposome vesicles

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