Two new sesquiterpene lactones from the supercritical fluid extract of Centipeda minima

摘要

Two new sesquiterpene lactones, minimolides G (1) and H (2), were isolated from the supercritical fluid extract of Centipeda minima. Their structures were elucidated on the basis of extensive analyses of spectroscopic data including IR, HR-ESI-MS, 1D and 2D NMR. Compounds 1 and 2 displayed inhibitory activity against human nasopharyngeal cancer cell line (CNE) with IC₅₀ values of 61.4 and 28.7 μM, respectively.View full textDownload full textKeywords Centipeda minima , sesquiterpene lactones, supercritical fluid extract, antiproliferative activityRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/10286020.2012.670222