The Statistics of Gene Mapping

摘要

In the last two decades, gene mapping with experimental and human popu-lations has progressed rapidly, and various approaches have been developed for complex trait mapping using molecular markers. Until now, textbook availabil-ity has been limited, so The Statistics of Gene Mapping (SGM) is a welcome addition to the statistical genetics literature.rnThe authors' summary states that "This book presents a unified discussion of the statistical concepts applied to gene mapping, first in the experimental context of crosses of inbred lines and then in outbred populations, primarily humans." The book focuses on statistical issues and assumes that readers have some familiarity with elementary genetics. Those who make it to the finish line will have a solid understanding of the statistical challenges involved in gene mapping.