Regio- and Stereoselective Ring-Opening Cross-Metathesis. Rapid Entry into Functionalized Bicyclo[6.3.0] Ring Systems

摘要

In summary, several key issues have been documented here. First, as illustrated in Scheme 1, ring-opening cross-metathesis between cyclobutene-containing substrates and ethylene pro- ceeds readily and selectively. Second, local chirality plays a crucial role in determining the facility and selectivity with which ring-opening cross-metathesis of functionalized cyclobutenes take place (Table 1).